Tislelizumab |CAS:1858168-59-8 Probechem Biochemicals

Chemical Structure : Tislelizumab

CAS No.: 1858168-59-8

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Tislelizumab (Anti-human PD-1 mAb, human IgG4P-Kappa; BGB-A317)

货号: PC-Ab1067Not For Human Use, Lab Use Only.

Tislelizumab (BGB-A317) is a humanized IgG4 anti-PD-1 monoclonal antibody specifically designed to minimize binding to FcγR on macrophages. Tislelizumab (BGB-A317) binds to and blocks human PD-1 with high affinity and specificity, shows anti-tumor activity through activation of antibody-dependent macrophage-mediated killing of T effector cells..

规格	价格	库存
1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量
分子式	Human IgG4P-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Tislelizumab; Tilelizumab; Tirelizumab; BGB-A317; CD279; programmed death-1; programmed death 1 ; anti-PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1

参考文献

1. 1, Liu SY, et al. Expert Opin Investig Drugs. 2020 Dec;29(12):1355-1364. 2, Xu J, et al. Clin Cancer Res. 2020 Sep 1;26(17):4542-4550. 3, Shen L, et al. J Immunother Cancer. 2020 Jun;8(1):e000437. 4, Friedlander M, et al. Lancet Oncol. 2019 Sep;20(9):1306-1315. 5, Song Y, et al. Leukemia. 2020 Feb;34(2):533-542.

Tislelizumab (Anti-human PD-1 mAb, human IgG4P-Kappa; BGB-A317)

生物&药学活性

物理化学性质&存储条件

参考文献

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Tislelizumab (Anti-human PD-1 mAb, human IgG4P-Kappa; BGB-A317)

生物&药学活性

物理化学性质&存储条件

参考文献

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