Tilpisertib fosmecarbil | TPL2 inhibitor | Probechem Biochemicals

Chemical Structure : Tilpisertib fosmecarbil

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货号: PC-27855Not For Human Use, Lab Use Only.

Tilpisertib fosmecarbil (GS-5290) is an intestinally cleaved prodrug of GS-4875, a potent tumor progression locus 2 (TPL2 , COT, MAP3K8) inhibitor.

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Tilpisertib fosmecarbil (GS-5290) is an intestinally cleaved prodrug of GS-4875, a potent tumor progression locus 2 (TPL2 , COT, MAP3K8) inhibitor.

分子量	747.15
分子式	C35H36ClN8O7P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(phosphonooxy)methyl (S)-((1-(bicyclo[1.1.1]pentan-1-yl)-1H-1,2,3-triazol-4-yl)(2-methyl-1-oxo-1,2-dihydroisoquinolin-5-yl)methyl)(8-chloro-3-cyano-4-(neopentylamino)quinolin-6-yl)carbamate

1. Priyanka A Madia, et al. J Clin Pharmacol. 2026 Aug;66(8):e70269.