TiY | Probechem Biochemicals

Chemical Structure : TiY

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TiY (TIC Fluorescent Probe TiY)

货号: PC-62598Not For Human Use, Lab Use Only.

TiY (TIC Fluorescent Probe TiY) is the first TIC (tumor initiating cell)-specific fluorescent chemical probe, target vimentin, a marker for epithelial-to-mesenchymal transition (EMT).

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生物&药学活性

TiY (TIC Fluorescent Probe TiY) is the first TIC (tumor initiating cell)-specific fluorescent chemical probe, target vimentin, a marker for epithelial-to-mesenchymal transition (EMT); selectively stains TICs over differentiated tumor cells or normal cells, and facilitates the visualization and enrichment of functionally active TICs from patient tumors; also shows anti-TIC activity with low toxicity to non-TICs at high concentration.

物理化学性质&存储条件

分子量	541.875
分子式	C29H35BClF2N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(2-(3-(3-(tert-butyl)-2-propoxystyryl)-5,5-difluoro-1-methyl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)ethyl)-2-chloroacetamide

参考文献

1. Lee YA, et al. Angew Chem Int Ed Engl. 2018 Jan 26.

TiY (TIC Fluorescent Probe TiY)

生物&药学活性

物理化学性质&存储条件

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TiY (TIC Fluorescent Probe TiY)

生物&药学活性

物理化学性质&存储条件

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