Chemical Structure : Thiostrepton
CAS No.: 1393-48-2
货号: PC-26220Not For Human Use, Lab Use Only.
Thiostrepton is a thiazole antibiotic that selectively inhibits FOXM1, also significantly inhibits ETV4 K97-Khib, thereby promoting ferroptosis and suppressing ICC cell migration, invasion, and lung metastasis.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 mg | ¥580 | In stock | |
| 250 mg | ¥880 | In stock | |
| 1 g | Get quote |
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Thiostrepton is a thiazole antibiotic that selectively inhibits FOXM1, also significantly inhibits ETV4 K97-Khib, thereby promoting ferroptosis and suppressing ICC cell migration, invasion, and lung metastasis.
| 分子量 | 1664.89 | |
| 分子式 | C72H85N19O18S5 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[(7R,8S)-2-Carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-isoleucyl-L-alanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexadecahydro-11,28-bis[(1R)-1-hydroxyethyl]-9,12,19,26-tetraoxo-17H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-4-thiazolecarbonyl-2,3-didehydroala |
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1. Ajaybabu V Pobbati, et al. Theranostics. 2020 Feb 18;10(8):3622-3635.
2. Xuan Zhang, et al. Oncotarget. 2014 Nov 30;5(22):11365-80.
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