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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-Thienopyridone
Thienopyridone

Chemical Structure : Thienopyridone

CAS No.: 1018454-97-1

Thienopyridone

货号: PC-22856Not For Human Use, Lab Use Only.

Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatases inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3), respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatases inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3), respectively.

物理化学性质&存储条件

分子量 242.30
分子式 C13H10N2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-Amino-2-phenylthieno[3,2-c]pyridin-4(5H)-one

参考文献

1. Daouti S, et al. Cancer Res. 2008 Feb 15;68(4):1162-9.

2. Kostantin E, et al. J Biol Chem. 2016 May 13;291(20):10716-25.

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