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首页-小分子抑制剂&激动剂-Others-Other Targets-Thiazolidine-2-carboxylate
Thiazolidine-2-carboxylate

Chemical Structure : Thiazolidine-2-carboxylate

CAS No.: 16310-13-7

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Thiazolidine-2-carboxylate (T2C)

货号: PC-27845Not For Human Use, Lab Use Only.

Thiazolidine-2-carboxylate (T2C) is a covalent, irreversible inhibitor of proline dehydrogenase (PRODH), covalently binds to the N5 of the FAD in the PRODH domain. also inhibits pyrroline-5-carboxylate reductase 1 (PYCR1).

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50 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Thiazolidine-2-carboxylate (T2C) is a covalent, irreversible inhibitor of proline dehydrogenase (PRODH), covalently binds to the N5 of the FAD in the PRODH domain. also inhibits pyrroline-5-carboxylate reductase 1 (PYCR1).

物理化学性质&存储条件

分子量 133.17
分子式 C4H7NO2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

thiazolidine-2-carboxylic acid

参考文献

1. Campbell AC, et al. ACS Chem Biol. 2020 Apr 17;15(4):936-944.

2. Scott GK, et al. Amino Acids. 2021 Dec;53(12):1927-1939.

3. Christensen EM, et al. J Biol Chem. 2020 Dec 25;295(52):18316-18327.

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