Tezampanel |CAS:150131-78-5 Probechem Biochemicals

Chemical Structure : Tezampanel

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Tezampanel (LY 293558;NGX 424)

货号: PC-61713Not For Human Use, Lab Use Only.

Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor.

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生物&药学活性

Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor.
Tezampanel (LY 293558, NGX 424) has neuroprotective and anticonvulsant properties, also has anxiolytic effects in animal studies.

物理化学性质&存储条件

分子量	279.344
分子式	C13H21N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,4aR,6R,8aR)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid

参考文献

1. Ornstein PL, et al. J Med Chem. 1993 Jul 9;36(14):2046-8.

2. LeBlanc MH, et al. Stroke. 1995 Oct;26(10):1908-14; discussion 1914-5.

3. Benvenga MJ, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):164-70.

Tezampanel (LY 293558;NGX 424)

生物&药学活性

物理化学性质&存储条件

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Tezampanel (LY 293558;NGX 424)

生物&药学活性

物理化学性质&存储条件

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