Tetrandrine |CAS:518-34-3 Probechem Biochemicals

Chemical Structure : Tetrandrine

CAS No.: 518-34-3

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Tetrandrine (NSC 77037, Fanchinine)

货号: PC-62318Not For Human Use, Lab Use Only.

Tetrandrine (NSC 77037, Fanchinine) is a bis-benzylisoquinoline alkaloid that acts a calcium channel blocker (IC50= 8 and 20 uM for L-type and T-type calcium channels, respectively) and induces apoptosis.

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500 mg	￥780	In stock
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生物&药学活性

Tetrandrine (NSC 77037, Fanchinine) is a bis-benzylisoquinoline alkaloid that acts a calcium channel blocker (IC50= 8 and 20 uM for L-type and T-type calcium channels, respectively) and induces apoptosis.
Tetrandrine produces anti-inflammatory, immunomodulating, anti-proliferative, and free radical scavenging effects.
Tetrandrine has also been shown to increase glucose utilization by enhancing hepatocyte glycogen synthesis.
Tetrandrine is a potent cell autophagy agonist, is also a potent CAMKIIdelta inhibitor.

物理化学性质&存储条件

分子量	622.8
分子式	C38H42N2O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	d-tetrandrine

参考文献

1. Xie QM, et al. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13.

2. Yang Z, et al. Sci Rep. 2016 Jul 26;6:30263.

3. Wang H, et al. Cell Biosci. 2015 Jan 14;5:4.

Tetrandrine (NSC 77037, Fanchinine)

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物理化学性质&存储条件

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Tetrandrine (NSC 77037, Fanchinine)

生物&药学活性

物理化学性质&存储条件

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