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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-Tetrabenazine
Tetrabenazine

Chemical Structure : Tetrabenazine

CAS No.: 58-46-8

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Tetrabenazine (Ro 1-9569)

货号: PC-24214Not For Human Use, Lab Use Only.

Tetrabenazine (Ro 1-9569) is a potent, reversible inhibitor of the vesicular monoamine transporter VMAT2 with Kd of 1.34 nM, shows potential for diseases related to hyperactive movement disorders such as Huntington's disease.

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500 mg ￥980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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Tetrabenazine (Ro 1-9569) is a potent, reversible inhibitor of the vesicular monoamine transporter VMAT2 with Kd of 1.34 nM, shows potential for diseases related to hyperactive movement disorders such as Huntington's disease.

物理化学性质&存储条件

分子量 317.43
分子式 C19H27NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

rel-(3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one

参考文献

1. J C Shih, et al. Brain Res. 1999 Jul 24;835(2):104-12.

2. Nobue Kitanaka, et al. Pharmacol Biochem Behav. 2018 Sep;172:9-16.

3. S J Podurgiel, et al. Neuroscience. 2013 Oct 10;250:507-19.

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