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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-Tetomilast
Tetomilast

Chemical Structure : Tetomilast

CAS No.: 145739-56-6

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Tetomilast (OPC-6535, OPC6535)

货号: PC-63093Not For Human Use, Lab Use Only.

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release.
Tetomilast attenuates sepsis-induced acute lung injury.

物理化学性质&存储条件

分子量 370.42
分子式 C19H18N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid

参考文献

1. Schreiber S, et al. Gastroenterology. 2007 Jan;132(1):76-86.

2. Bloomfield GL, et al. J Surg Res. 1997 Sep;72(1):70-7.

3. Ejiri S, et al. Transplant Proc. 2000 Mar;32(2):318-21.

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