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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-Tertiapin-Q
Tertiapin-Q

Chemical Structure : Tertiapin-Q

CAS No.: 910044-56-3

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Tertiapin-Q

货号: PC-22937Not For Human Use, Lab Use Only.

Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and renal outer medullary potassium channel (ROMK1, Kir1.1), blocks recombinant and native large conductance K+ channels.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and renal outer medullary potassium channel (ROMK1, Kir1.1), blocks recombinant and native large conductance K+ channels.

物理化学性质&存储条件

分子量 2452.00
分子式 C106H175N35O24S4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridge: Cys3-Cys14, Cys5-Cys18)

参考文献

1. Picton LD, et al. Sci Rep. 2016 Oct 20;6:35749.

2. Sackin H, et al. Biophys J. 2003 Feb;84(2 Pt 1):910-21.

3. Jin W, et al. Biochemistry. 1999 Oct 26;38(43):14294-301.

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