Teriflunomide (RS-61980, A771726)

Chemical Structure : Teriflunomide

CAS No.: 163451-81-8

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货号: PC-20268Not For Human Use, Lab Use Only.

Teriflunomide (RS-61980, A771726) is the active metabolite of leflunomide, acts as an immunomodulatory agent by inhibiting pyrimidine synthesis, inhibits dihydroortate dehydrogenase (DHODH, EC 1.3.3.1) with IC50 of 2.7 uM.

规格	价格	库存
50 mg	￥580	In stock
100 mg	￥880	In stock
500 mg	￥1880	In stock
1 g		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	270.21
分子式	C12H9F3N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide

参考文献

1. Patterson JW, et al. J Med Chem. 1992 Feb 7;35(3):507-10.

2. Greene S, et al. Biochem Pharmacol. 1995 Sep 7;50(6):861-7.