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首页-小分子抑制剂&激动剂-GPCR-Angiotensin Receptor-Telmisartan
Telmisartan

Chemical Structure : Telmisartan

CAS No.: 144701-48-4

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Telmisartan (BIBR-277, BIBR277)

货号: PC-24210Not For Human Use, Lab Use Only.

Telmisartan (BIBR-277) is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), inhibits binding of 125I-AngII to AT1 receptor with IC50 of 9.2 nM.

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100 mg ￥680 In stock
500 mg ￥1180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Telmisartan (BIBR-277) is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), inhibits binding of 125I-AngII to AT1 receptor with IC50 of 9.2 nM.

物理化学性质&存储条件

分子量 514.63
分子式 C33H30N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid

参考文献

1. Maillard MP, et al. J Pharmacol Exp Ther. 2002 Sep;302(3):1089-95.

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