Tec Kinase-IN-6 |CAS:923762-87-2 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Tyrosine Kinase-Tec Kinase-Tec Kinase-IN-6

Chemical Structure : Tec Kinase-IN-6

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Tec Kinase-IN-6

货号: PC-60852Not For Human Use, Lab Use Only.

Tec Kinase-IN-6 is a selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM.

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1 g		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Tec Kinase-IN-6 is a selecitve small molecule toward Tec kinase-mediated tyrosine phosphorylation of FGF2 with IC50 of 8.9 uM.
Tec Kinase-IN-6 inhibits Tec-FGF2 complex and blocks tyrosine phosphorylation of FGF2 in cells, also inhibit FGF2 secretion from cells.

物理化学性质&存储条件

分子量	369.377
分子式	C19H19N3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-methyl 2-((6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl) 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate

参考文献

1. La Venuta G, et al. J Biol Chem. 2016 Aug 19;291(34):17787-803.

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Tec Kinase-IN-6

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