Tauroursodeoxycholic acid sodium |CAS:35807-85-3 Probechem Biochemicals

Chemical Structure : Tauroursodeoxycholic acid sodium

CAS No.: 35807-85-3

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Tauroursodeoxycholic acid sodium (TUDCA)

货号: PC-45672Not For Human Use, Lab Use Only.

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.

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100 mg	￥780	In stock
500 mg	￥1380	In stock
1 g		Get quote

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生物&药学活性

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.
TUDCA inhibits nuclear factor-kappa B (NF-κB) activation in glial cells.
TUDCA shows anti-inflammatory effect by inducing TGF-β pathway.
TUDCA also inhibits TNFα-induced lipolysis.

物理化学性质&存储条件

分子量	521.6854
分子式	C26H44NNaO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: ≥ 39 mg/mL
Chemical Name/SMILES	Ethanesulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

参考文献

1. Romero-Ramirez L, et al. Neural Regen Res. 2017 Jan;12(1):62-63.

2. Xia W, et al. Mol Med Rep. 2017 Apr;15(4):1753-1758.

3. Rani S, et al. PLoS One. 2017 Apr 20;12(4):e0176071.

Tauroursodeoxycholic acid sodium (TUDCA)

生物&药学活性

物理化学性质&存储条件

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Tauroursodeoxycholic acid sodium (TUDCA)

生物&药学活性

物理化学性质&存储条件

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