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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-Taspoglutide
Taspoglutide

Chemical Structure : Taspoglutide

CAS No.: 275371-94-3

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Taspoglutide (ITM-077, R-1583, BIM-51077)

货号: PC-47502Not For Human Use, Lab Use Only.

Taspoglutide (ITM-077, R-1583, BIM-51077) is a glucagon-like peptide-1(GLP-1) agonist with EC50 of 0.06 nM, shows potential for treatment of type 2 diabetes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Taspoglutide (ITM-077, R-1583, BIM-51077) is a glucagon-like peptide-1(GLP-1) agonist with EC50 of 0.06 nM, shows potential for treatment of type 2 diabetes.
Phase III clinical trials halted due to incidences of side effects.

物理化学性质&存储条件

分子量 3339.709
分子式 C152H232N40O45
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 28 mg/mL
Chemical Name/SMILES

7-36-Glucagon-like peptide I (human), 8-(2-methylalanine)-35-(2-methylalanine)-36-L-argininamide-

参考文献

1. Dong JZ, et al. Diabetes Obes Metab. 2011 Jan;13(1):19-25.

2. Giraudon M, et al. Diabetes Obes Metab. 2017 Apr;19(4):537-544.

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