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Tapencarium

Chemical Structure : Tapencarium

CAS No.: 1436920-57-8

Tapencarium (Utenpanium chloride, RZL-012, RZL012)

货号: PC-24192Not For Human Use, Lab Use Only.

Tapencarium (Utenpanium chloride, RZL-012) is a fat-reducing and small molecule thermogenic regulator, destroys adipocytes by directly disrupting cell membrane integrity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Tapencarium (Utenpanium chloride, RZL-012) is a fat-reducing and small molecule thermogenic regulator, destroys adipocytes by directly disrupting cell membrane integrity.
RZL-012 triggered adipocyte cell killing with IC50 values ranging from 25 to 106 μM.
RZL-012 demonstrated initial effects on membrane integrity and calcium levels with delayed alterations in mitochondrial membrane potential (MMP).
RZL-012 may potentially be used for the treatment of Dercum's Disease lipomas.

物理化学性质&存储条件

分子量 488.69
分子式 C20H25Br2ClN2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9H-Carbazole-9-pentanaminium, 3,6-dibromo-N,N,N-trimethyl-, chloride (1:1)

参考文献

1. Blaugrund E, et al. Dermatol Surg. 2021 Dec 1;47(12):1601-1605.

2. Shridharani SM, et al. Aesthet Surg J. 2023 Sep 14;43(10):NP797-NP806.

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