Tanomastat |CAS:179545-77-8 Probechem Biochemicals

Chemical Structure : Tanomastat

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Tanomastat (BAY129566;BAY 12-9566)

货号: PC-62947Not For Human Use, Lab Use Only.

Tanomastat (BAY 129566) is a potent,orally available, non-peptidic inhibitor of MMP-2, MMP-3 and MMP-9 with 11, 143 and 301 nM, respectively.

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生物&药学活性

Tanomastat (BAY 129566) is a potent,orally available, non-peptidic inhibitor of MMP-2, MMP-3 and MMP-9 with 11, 143 and 301 nM, respectively.
Tanomastat inhibits extracellular matrix degradation and potentially inhibiting angiogenesis, tumor growth and invasion, and metastasis both in vitro and in vivo.

物理化学性质&存储条件

分子量	410.912
分子式	C23H19ClO3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(4'-chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid

参考文献

1. Gatto C, et al. Clin Cancer Res. 1999 Nov;5(11):3603-7.

2. Rowinsky EK, et al. J Clin Oncol. 2000 Jan;18(1):178-86.

3. Leung D, et al. J Med Chem. 2000 Feb 10;43(3):305-41.

4. Moore MJ, et al. J Clin Oncol. 2003 Sep 1;21(17):3296-302.

Tanomastat (BAY129566;BAY 12-9566)

生物&药学活性

物理化学性质&存储条件

参考文献

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Tanomastat (BAY129566;BAY 12-9566)

生物&药学活性

物理化学性质&存储条件

参考文献

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