Taniborbactam hydrochloride | Beta-lactamase inhibitor

Chemical Structure : Taniborbactam hydrochloride

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Taniborbactam hydrochloride (VNRX-5133 hydrochloride)

货号: PC-23182Not For Human Use, Lab Use Only.

Taniborbactam (VNRX5133) hydrochloride is a highly potent and specific beta-lactamase inhibitor with IC50 of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2 respectively.

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生物&药学活性

Taniborbactam (VNRX5133) hydrochloride is a highly potent and specific beta-lactamase inhibitor with IC50 of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2 respectively.
Taniborbactam (VNRX5133) shows activity against Gram-negative bacteria and used in combination with a licensed beta-lactam antibiotic.

物理化学性质&存储条件

分子量	462.18
分子式	C19H28BN3O5.2ClH
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-1,2-Benzoxaborin-8-carboxylic acid, 3-[[2-[trans-4-[(2-aminoethyl)amino]cyclohexyl]acetyl]amino]-3,4-dihydro-2-hydroxy-, hydrochloride (1:2), (3R)-

参考文献

1. Krajnc A, et al. J Med Chem. 2019 Sep 26;62(18):8544-8556.

Taniborbactam hydrochloride (VNRX-5133 hydrochloride)

生物&药学活性

物理化学性质&存储条件

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Taniborbactam hydrochloride (VNRX-5133 hydrochloride)

生物&药学活性

物理化学性质&存储条件

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