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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Estrogen Receptor/ERR-Tamoxifen
Tamoxifen

Chemical Structure : Tamoxifen

CAS No.: 10540-29-1

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Tamoxifen (ICI 47699, (Z)-Tamoxifen, Trans-tamoxifen)

货号: PC-28232Not For Human Use, Lab Use Only.

Tamoxifen (ICI 47699) is a nonsteroidal antiestrogen and orally active, selective estrogen receptor modulator (SERM), targets estrogen binding to ER,  also inhibits the activity of PKC and inhibits cancer cell proliferation, is used mainly for the treatment of breast cancer.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Tamoxifen (ICI 47699) is a nonsteroidal antiestrogen and orally active, selective estrogen receptor modulator (SERM), targets estrogen binding to ER,  also inhibits the activity of PKC and inhibits cancer cell proliferation, is used mainly for the treatment of breast cancer.

物理化学性质&存储条件

分子量 371.52
分子式 C26H29NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

参考文献

1. Osborne CK. N Engl J Med. 1998 Nov 26;339(22):1609-18.

2. Hawariah A, et al Anticancer Res. 1998 Nov-Dec;18(6A):4383-6.

3. Huet S, et al. Eur J Cancer. 1993;29A(10):1377-83.

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