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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase-Takeda-17
Takeda-17

Chemical Structure : Takeda-17

CAS No.: 2009343-14-8

Takeda-17 (PHD-1 inhibitor 17)

货号: PC-23636Not For Human Use, Lab Use Only.

Takeda-17 (PHD-1 inhibitor 17) is a potent, selective inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) with IC50 of 34 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Takeda-17 (PHD-1 inhibitor 17) is a potent, selective inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) with IC50 of 34 nM.

物理化学性质&存储条件

分子量 220.24
分子式 C13H8N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile

参考文献

1. Ahmed S, et al. J Med Chem. 2017 Jul 13;60(13):5663-5672.

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