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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-Tadalafil
Tadalafil

Chemical Structure : Tadalafil

CAS No.: 171596-29-5

Tadalafil (IC-351, IC351)

货号: PC-46014Not For Human Use, Lab Use Only.

Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
Tadalafil shows no inhibition on most of the other families of PDEs, with the exception of PDE11.

物理化学性质&存储条件

分子量 389.404
分子式 C22H19N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 52 mg/mL

Chemical Name/SMILES

Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-

参考文献

1. Blount MA, et al. Mol Pharmacol, 2004, 66(1), 144-152.

2. Ring BJ, et al. Clin Pharmacol Ther, 2005, 77(1), 63-75.

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