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首页-小分子抑制剂&激动剂-Others-Amyloids-TZ095
TZ095

Chemical Structure : TZ095

CAS No.: 2972464-50-7

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TZ095 (TZ-095)

货号: PC-23221Not For Human Use, Lab Use Only.

TZ095 is a coumarin-based Aβ fluorescent probe for precise Aβ detection, exhibits remarkable affinity with Aβ aggregates (Kd = 81.54 nM for oligomers; Kd = 66.70 nM for fibril) and substantial fluorescence enhancement (F/F0 = 44).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TZ095 is a coumarin-based Aβ fluorescent probe for precise Aβ detection, exhibits remarkable affinity with Aβ aggregates (Kd = 81.54 nM for oligomers; Kd = 66.70 nM for fibril) and substantial fluorescence enhancement (F/F0 = 44).

物理化学性质&存储条件

分子量 316.36
分子式 C20H16N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-7-(4-(dimethylamino)styryl)-2-oxo-2H-chromene-3-carbonitrile

参考文献

1. You H, et al. Eur J Med Chem. 2024 Nov 15;278:116800.

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