TYK2-JH1 inhibitor 30

Chemical Structure : TYK2-JH1 inhibitor 30

CAS No.: 2244061-66-1

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货号: PC-49112Not For Human Use, Lab Use Only.

TYK2-JH1 inhibitor 30 is a potent and selective TYK2-JH1 inhibitor with Ki of 0.51 nM.

规格	价格	库存
5 mg	￥2480	In stock
10 mg	￥3980	In stock
25 mg	￥5980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

TYK2-JH1 inhibitor 30 is a potent and selective TYK2-JH1 inhibitor with Ki of 0.51 nM.
TYK2-JH1 inhibitor 30 shows excellent selectivity, pharmacokinetic properties, and in vivo efficacy in a mouse psoriasis model.

物理化学性质&存储条件

分子量	434.447
分子式	C24H20F2N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2,6-difluorophenyl)-4-((4-(pyrrolidine-1-carbonyl)phenyl)amino)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

参考文献

1. Silvana Leit, et al. Bioorg Med Chem Lett. 2022 Jul 13;73:128891.