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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-TXA6101
TXA6101

Chemical Structure : TXA6101

CAS No.: 1459695-66-9

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TXA6101 (TXA 6101)

货号: PC-49163Not For Human Use, Lab Use Only.

TXA6101 is an FtsZ-targeting compound with activity against MRSA isolates that express either G196S or G193D mutant FtsZ proteins, shows potent in vitro antibacterial activity against MRSA clinical isolate MPW020 with MIC of 0.125 ug/mL.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TXA6101 is an FtsZ-targeting compound with activity against MRSA isolates that express either G196S or G193D mutant FtsZ proteins, shows potent in vitro antibacterial activity against MRSA clinical isolate MPW020 with MIC of 0.125 ug/mL.
    TXA6101 is active against both FtsZ mutant strains (G196S and G193D mutant FtsZ) with MIC of 1 ug/mL, but TXA707 is inactive.

    物理化学性质&存储条件

    分子量 477.185
    分子式 C18H10BrF5N2O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-((5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)methoxy)-2,6-difluorobenzamide

    参考文献

    1. Fujita J, et al. ACS Chem Biol. 2017 Jul 21;12(7):1947-1955.

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