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首页-小分子抑制剂&激动剂-GPCR-Free Fatty Acid Receptor (FFAR)-TUG-424
TUG-424

Chemical Structure : TUG-424

CAS No.: 1082058-99-8

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TUG-424 (TUG424)

货号: PC-20421Not For Human Use, Lab Use Only.

TUG-424 (TUG424) is a potent, selective free fatty acid receptor 1 (FFA1, GPR40) agonist with EC50 of 32 nM, TUG-424 (100 nM) enhances glucose-stimulated insulin secretion from rat INS-1E cells and isolated mouse islets.

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5 mg ￥2280 In stock
10 mg ￥3780 In stock
25 mg ￥5980 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TUG-424 (TUG424) is a potent, selective free fatty acid receptor 1 (FFA1, GPR40) agonist with EC50 of 32 nM, TUG-424 (100 nM) enhances glucose-stimulated insulin secretion from rat INS-1E cells and isolated mouse islets.

物理化学性质&存储条件

分子量 264.32
分子式 C18H16O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-[2-(2-Methylphenyl)ethynyl]benzenepropanoic acid

参考文献

1. Christiansen E, et al. J Med Chem. 2008 Nov 27;51(22):7061-4.

2. Moodaley R, et al. Br J Pharmacol. 2017 Dec;174(23):4508-4522.

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