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首页-小分子抑制剂&激动剂-GPCR-Free Fatty Acid Receptor (FFAR)-TUG-2304
TUG-2304

Chemical Structure : TUG-2304

CAS No.:

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TUG-2304 (TUG2304)

货号: PC-20767Not For Human Use, Lab Use Only.

TUG-2304 (TUG2304) is a highly potent FFA2 (GPR43) antagonist with IC50 of 3-4 nM in both cAMP and GTPγS assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TUG-2304 (TUG2304) is a highly potent FFA2 (GPR43) antagonist with IC50 of 3-4 nM in both cAMP and GTPγS assays.
    TUG-2304 completely inhibits propionate-induced neutrophil migration and respiratory burst in vivo. 

    物理化学性质&存储条件

    分子量 419.41
    分子式 C20H20F3N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-N-(1-(1H-tetrazol-5-yl)-3-(4-(trifluoromethyl)phenyl)propan-2-yl)-2-(3-methoxyphenyl)acetamide

    参考文献

    1. Alice Valentini, et al. J Med Chem. 2023 May 11;66(9):6105-6121.

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