TUDCA | Bax inhibitor | Probechem Biochemicals

Chemical Structure : TUDCA

CAS No.: 14605-22-2

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TUDCA (Tauroursodeoxycholic acid)

货号: PC-22111Not For Human Use, Lab Use Only.

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.

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50 mg	￥680	In stock
100 mg	￥980	In stock
200 mg	￥1380	In stock
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生物&药学活性

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.
TUDCA inhibits nuclear factor-kappa B (NF-κB) activation in glial cells.
TUDCA shows anti-inflammatory effect by inducing TGF-β pathway.
TUDCA also inhibits TNFα-induced lipolysis.

物理化学性质&存储条件

分子量	499.71
分子式	C26H45NO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid

参考文献

1. Romero-Ramirez L, et al. Neural Regen Res. 2017 Jan;12(1):62-63.

2. Xia W, et al. Mol Med Rep. 2017 Apr;15(4):1753-1758.

3. Rani S, et al. PLoS One. 2017 Apr 20;12(4):e0176071.

TUDCA (Tauroursodeoxycholic acid)

生物&药学活性

物理化学性质&存储条件

参考文献

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TUDCA (Tauroursodeoxycholic acid)

生物&药学活性

物理化学性质&存储条件

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