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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-TTS29
TTS29

Chemical Structure : TTS29

CAS No.: 1082953-49-8

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TTS29

货号: PC-27563Not For Human Use, Lab Use Only.

TTS29 is a small molecule inhibitor of S. typhimurium type III secretion system (T3SS), disrupts the needle assembly of Yersinia spp., P. aeruginosa and Francisella novicida, block the secretion and virulence functions of a wide array of animal and plant Gram-negative bacterial pathogens, such as Y. spp., P. aeruginosa and Francisella novicida.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TTS29 is a small molecule inhibitor of S. typhimurium type III secretion system (T3SS), disrupts the needle assembly of Yersinia spp., P. aeruginosa and Francisella novicida, block the secretion and virulence functions of a wide array of animal and plant Gram-negative bacterial pathogens, such as Y. spp., P. aeruginosa and Francisella novicida.

物理化学性质&存储条件

分子量 432.49
分子式 C24H20N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(Z)-5-((Z)-4-hydroxy-3,5-dimethoxybenzylidene)-3-phenyl-2-(phenylimino)thiazolidin-4-one

参考文献

1. Gu L, et al. Molecules (Basel, Switzerland) 2015;20(9):17659–17674.

2. Kline T, et al. Bioorg. Med. Chem. Lett. 2009;19:1340–1343.

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