TTK21 |CAS:709676-56-2 Probechem Biochemicals

Chemical Structure : TTK21

CAS No.: 709676-56-2

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TTK21 (CBP-p300 activator TTK21)

货号: PC-36166Not For Human Use, Lab Use Only.

TTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3280	In stock
50 mg	￥5280	In stock
100 mg		Get quote

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生物&药学活性

TTK21 (CBP-p300 activator TTK21) is a small molecule activator of CBP/p300 histone acetyltransferase activity with a maximal effect at a concentration of 275 uM.
TTK21 induces acetylation of histones H3 and H4 in vitro but not H2B and H2A.
TTK21 promotes neurogenesis and extends memory duration in adult mice, promotes regeneration and sprouting of sensory and motor axons, as well as recovery of sensory and motor functions in both the mouse and rat model of spinal cord injury.

物理化学性质&存储条件

分子量	357.757
分子式	C17H15ClF3NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-chloro-3-trifluoromethyl-phenyl)-2-N-propoxy-benzamide

参考文献

1. Chatterjee S, et al. J Neurosci. 2013 Jun 26;33(26):10698-712.

2. Hutson TH, et al. Sci Transl Med. 2019 Apr 10;11(487). pii: eaaw2064.

TTK21 (CBP-p300 activator TTK21)

生物&药学活性

物理化学性质&存储条件

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TTK21 (CBP-p300 activator TTK21)

生物&药学活性

物理化学性质&存储条件

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