TTGM 5826 |CAS:330471-93-7 Probechem Biochemicals

Chemical Structure : TTGM 5826

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TTGM 5826 (TTGM-5826;TTGM5826)

货号: PC-35734Not For Human Use, Lab Use Only.

TTGM 5826 (TTGM5826, TTGM-5826) is a small molecule, potential modulator of tissue transglutaminase (tTG) conformation.

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生物&药学活性

TTGM 5826 (TTGM5826, TTGM-5826) is a small molecule, potential modulator of tissue transglutaminase (tTG) conformation.
TTGM 5826 broadly inhibits the transformed phenotypes of breast and brain cancer cell lines, as well as glioma stem cells.
TTGM 5826 promotes the toxicity of cancer cells by stabilizing the open state of tTG.

物理化学性质&存储条件

分子量	480.48
分子式	C27H20N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-5-(((3-((1,3-dioxoisoindolin-2-yl)methyl)-4-methylphenyl)amino)methylene)-1-phenylpyrimidine-2,4,6(1H,3H,5H)-trione

参考文献

1. Katt WP, et al. Oncotarget. 2018 Sep 28;9(76):34379-34397.

TTGM 5826 (TTGM-5826;TTGM5826)

生物&药学活性

物理化学性质&存储条件

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TTGM 5826 (TTGM-5826;TTGM5826)

生物&药学活性

物理化学性质&存储条件

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