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首页-小分子抑制剂&激动剂-Others-Other Targets-TTFB
TTFB

Chemical Structure : TTFB

CAS No.: 352560-76-0

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TTFB (ZAC antagonist TTFB)

货号: PC-72756Not For Human Use, Lab Use Only.

TTFB (ZAC antagonist TTFB) is a selective antagonist (negative allosteric modulator) of Zinc-Activated Channel (ZAC) with IC50 of 3 uM.

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10 mg ￥2280 In stock
50 mg ￥6280 In stock
100 mg ￥10800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TTFB (ZAC antagonist TTFB) is a selective antagonist (negative allosteric modulator) of Zinc-Activated Channel (ZAC) with IC50 of 3 uM.
TTFB dispalys no significant agonist, antagonist or modulatory activity on a panel of four classical CLR subfamilies: the m5-HT3AR, the hα3β4 nAChR, the hα1β2γ2S GABAAR and the hα1 GlyR.
TTFB mediates equipotent and voltage-independent inhibition of agonist-evoked and spontaneous ZAC signaling.

物理化学性质&存储条件

分子量 278.345
分子式 C14H15FN2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

参考文献

1. Nawid Madjroh, et al. Biochem Pharmacol. 2021 Nov;193:114782.

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