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TRiCi

Chemical Structure : TRiCi

CAS No.: 29308-14-3

TRiCi (TRiC inhibitor)

货号: PC-28626Not For Human Use, Lab Use Only.

TRiC inhibitor (TRiCi) is specific small molecule inhibitor of TRiC subunit TCP1, inhibits archaeal TCP1 activity in vitro, inducing decrease in CSA levels while not affecting TCP1 levels.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TRiC inhibitor (TRiCi) is specific small molecule inhibitor of TRiC subunit TCP1, inhibits archaeal TCP1 activity in vitro, inducing decrease in CSA levels while not affecting TCP1 levels.
TRiC is a eukaryotic chaperonin that has evolved to ensure proteome integrity of essential and topologically complex proteins, including cell-cycle regulators, signaling proteins, and cytoskeletal components.

物理化学性质&存储条件

分子量 244.65
分子式 C8H5ClN2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(4-chloro-2,1,3-benzothiadiazol-5-yl)oxy]acetic acid

参考文献

1. Alex Pines, et al. Nat Commun. 2018 Mar 12;9(1):1040.

2. Meng X, et al. Mol Cell. 2026 Apr 2;86(7):1327-1344.e10.

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