TRPM5 agonist 39

Chemical Structure : TRPM5 agonist 39

CAS No.:

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货号: PC-49536Not For Human Use, Lab Use Only.

TRPM5 agonist 39 is a potent, selective transient receptor potential cation channel subfamily M member 5 (TRPM5) agonist with pEC50 of 7.1, shows high selectivity over TRPA1, TRPV1, TRPV4, TRPM4 and TRPM8.

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生物&药学活性

TRPM5 agonist 39 is a potent, selective transient receptor potential cation channel subfamily M member 5 (TRPM5) agonist with pEC50 of 7.1, shows high selectivity over TRPA1, TRPV1, TRPV4, TRPM4 and TRPM8.

物理化学性质&存储条件

分子量	316.760
分子式	C17H14ClFN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R, 3R)-1-(3-chloro-5-fluorophenyl)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile

参考文献

1. M Sabat, et al. Bioorg Med Chem. 2022 Nov 6;76:117084.

TRPM5 agonist 39

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TRPM5 agonist 39

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