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首页-小分子抑制剂&激动剂-Others-Other Targets-TRF1-TIN2 interaction inhibitor 1
TRF1-TIN2 interaction inhibitor 1

Chemical Structure : TRF1-TIN2 interaction inhibitor 1

CAS No.:

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TRF1-TIN2 interaction inhibitor 1

货号: PC-25765Not For Human Use, Lab Use Only.

TRF1-TIN2 interaction inhibitor 1 (Compound 40) is a first-in-class inhibitor of the TRF1:TIN2 interaction with IC50 of 67 uM, binds to TRFH domain of TRF1 (TRF1 TRFH) with KD of 29 uM, disrupts shelterin complex assembly.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TRF1-TIN2 interaction inhibitor 1 (Compound 40) is a first-in-class inhibitor of the TRF1:TIN2 interaction with IC50 of 67 uM, binds to TRFH domain of TRF1 (TRF1 TRFH) with KD of 29 uM, disrupts shelterin complex assembly.

物理化学性质&存储条件

分子量 374.41
分子式 C19H18O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((3,5-dimethoxybenzyl)oxy)naphthalene-1-sulfonic acid

参考文献

1. Casale G, et al. Sci Rep. 2025 Nov 20;15(1):40922.

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