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首页-小分子抑制剂&激动剂-GPCR-Protease-activated Receptor (PAR)-TRAP-6
TRAP-6

Chemical Structure : TRAP-6

CAS No.: 141136-83-6

TRAP-6 (Thrombin Receptor Activator Peptide 6)

货号: PC-47484Not For Human Use, Lab Use Only.

TRAP-6 is a PAR1 peptide fragment (residues 42-47) that acts as a protease activating receptor 1 (PAR1) agonist, stimulates platelet aggregation (EC50=0.8 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TRAP-6 is a PAR1 peptide fragment (residues 42-47) that acts as a protease activating receptor 1 (PAR1) agonist, stimulates platelet aggregation (EC50=0.8 uM).
TRAP-6 promotes intracellular Ca2+ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation in vitro.

物理化学性质&存储条件

分子量 748.8701
分子式 C34H56N10O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 28 mg/mL

Chemical Name/SMILES

L-Asparagine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-

参考文献

1. Vassallo RR Jr, et al. J Biol Chem. 1992 Mar 25;267(9):6081-5.

2. Kaufmann R, et al. J Neurooncol. 1999 Apr;42(2):131-6.

3. Hunter RW, et al. J Biol Chem. 2009 May 1;284(18):12339-48.

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