Chemical Structure : TRAM-34
CAS No.: 289905-88-0
货号: PC-35994Not For Human Use, Lab Use Only.
TRAM-34 (TRAM34) is a potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (IKCa1) with Kd of 20 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥780 | In stock | |
25 mg | ¥1280 | In stock | |
50 mg | ¥1980 | In stock | |
100 mg | ¥3280 | In stock | |
250 mg | Get quote | ||
1 g | Get quote |
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TRAM-34 (TRAM34) is a potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (IKCa1) with Kd of 20 nM.
TRAM-34 displays 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels.
分子量 | 344.84 | |
分子式 | C22H17ClN2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole |
1. Wulff H, et al. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8151-6.
2. Köhler R, et al. Circulation. 2003 Sep 2;108(9):1119-25.
3. Wulff H, et al. J Biol Chem. 2001 Aug 24;276(34):32040-5.
4. Ghanshani S, et al. J Biol Chem. 2000 Nov 24;275(47):37137-49.
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