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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Tryptophan Hydroxylase (TPH)-TPH1-IN-1
TPH1-IN-1

Chemical Structure : TPH1-IN-1

CAS No.: 3040015-86-6

TPH1-IN-1

货号: PC-28320Not For Human Use, Lab Use Only.

TPH1-IN-1 is a potent small molecule inhibitor of Tryptophan hydroxylase 1 (TPH1) with IC50 of 110.1 nM, effectively suppresses the adipocyte differentiation of 3 T3-L1 cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TPH1-IN-1 is a potent small molecule inhibitor of Tryptophan hydroxylase 1 (TPH1) with IC50 of 110.1 nM, effectively suppresses the adipocyte differentiation of 3 T3-L1 cells.

物理化学性质&存储条件

分子量 450.47
分子式 C21H18N6O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Purine-2,6-dione, 3-ethyl-3,7-dihydro-7-[2-(4-hydroxyphenyl)-2-oxoethyl]-8-(imidazo[2,1-b]thiazol-6-ylmethyl)-

参考文献

1. Yoon J, et al. Bioorg Med Chem Lett. 2023 Oct 1;94:129461.

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