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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-TMX-3013
TMX-3013

Chemical Structure : TMX-3013

CAS No.: 2488761-18-6

TMX-3013 (TMX3013)

货号: PC-22926Not For Human Use, Lab Use Only.

TMX-3013 is a potent, multi-CDK inhibitor with IC50 of 0.9/<0.5/0.5/24.5/15.6 nM for CDK1/2/5/4/6 respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TMX-3013 is a potent, multi-CDK inhibitor with IC50 of 0.9/<0.5/0.5/24.5/15.6 nM for CDK1/2/5/4/6 respectively.

物理化学性质&存储条件

分子量 481.30
分子式 C17H14BrFN6O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((5-bromo-2-((4-sulfamoylphenyl)amino)pyrimidin-4-yl)amino)-6-fluorobenzamide

参考文献

1. Mingxing Teng, et al. Angew Chem Int Ed Engl. 2020 Aug 10;59(33):13865-13870.

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