TMX-2039 | pan CDK inhibitor | Probechem Biochemicals

Chemical Structure : TMX-2039

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TMX-2039 (TMX2039)

货号: PC-21527Not For Human Use, Lab Use Only.

TMX-2039 is a pan-CDK inhibitor with low nanomolar enzymatic IC50s (0.5-50 nM) for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9).

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生物&药学活性

TMX-2039 is a pan-CDK inhibitor with low nanomolar enzymatic IC50s (0.5-50 nM) for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9).

物理化学性质&存储条件

分子量	487.35
分子式	C17H20BrFN6O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((5-bromo-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-4-yl)amino)-6-fluorobenzamide

参考文献

1. Teng M, et al. Angew Chem Int Ed Engl. 2020 Aug 10;59(33):13865-13870.

TMX-2039 (TMX2039)

生物&药学活性

物理化学性质&存储条件

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TMX-2039 (TMX2039)

生物&药学活性

物理化学性质&存储条件

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