TMPyP4 tosylate |CAS:36951-72-1 Probechem Biochemicals

Chemical Structure : TMPyP4 tosylate

CAS No.: 36951-72-1

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TMPyP4 tosylate (TMP1363, TMP 1363)

货号: PC-62154Not For Human Use, Lab Use Only.

TMPyP4 tosylate (TMP1363) is a potent inhibitor of human telomerase with IC50 of 6.5 uM.

规格	价格	库存
50 mg	￥880	In stock
100 mg	￥1280	In stock
200 mg	￥1980	In stock
1 g		Get quote

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生物&药学活性

TMPyP4 tosylate (TMP1363) is a potent inhibitor of human telomerase with IC50 of 6.5 uM.
TMPyP4 tosylate (TMP1363) binds strongly to DNA quadruplexes by stacking on the G-tetrads at the core of the quadruplex, resulting in telomerase inhibition.
TMPyP4 tosylate (TMP1363) treatment causes reduction in telomere length, and decline of myeloma cell growth.

物理化学性质&存储条件

分子量	1363.6
分子式	C72H66N8O12S4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in H2O (13.6 mg/mL)
Chemical Name/SMILES	5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetra(p-toluenesulfonate)

参考文献

1. Phan AT, et al. Nat Chem Biol. 2005 Aug;1(3):167-73.

2. Shi DF, et al. J Med Chem. 2001 Dec 20;44(26):4509-23.

3. Shammas MA, et al. Mol Cancer Ther. 2003 Sep;2(9):825-33.

TMPyP4 tosylate (TMP1363, TMP 1363)

生物&药学活性

物理化学性质&存储条件

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TMPyP4 tosylate (TMP1363, TMP 1363)

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物理化学性质&存储条件

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