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TM-04-176-01

Chemical Structure : TM-04-176-01

CAS No.: 2428737-31-7

TM-04-176-01 (PI5P4K inhibitor 13, PI5P4Kα-IN-1)

货号: PC-38271Not For Human Use, Lab Use Only.

TM-04-176-01 (PI5P4K inhibitor 13) is a selective pan-PI5P4K covalent inhibitor with IC50 of 2.0/13 uM against PI5P4Kα/β, 100% inhibition of PI5P4Kγ at 1 uM (Kd=3.4 nM).

规格 价格 库存 数量
5 mg ¥2180 In stock
10 mg ¥3480 In stock
25 mg ¥5480 In stock
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100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TM-04-176-01 (PI5P4K inhibitor 13) is a selective pan-PI5P4K covalent inhibitor with IC50 of 2.0/13 uM against PI5P4Kα/β, 100% inhibition of PI5P4Kγ at 1 uM (Kd=3.4 nM).

物理化学性质&存储条件

分子量 363.435
分子式 C20H17N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(5-(1H-indol-4-yl)pyridin-3-yl)phenyl)methanesulfonamide

参考文献

1. Helen K Boffey, et al. J Med Chem. 2022 Feb 11. doi: 10.1021/acs.jmedchem.1c01819.

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