TLX agonist 2

Chemical Structure : TLX agonist 2

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货号: PC-27592Not For Human Use, Lab Use Only.

TLX agonist 2 (Compound 31) is a small molecule agonist of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 0.1 uM and Kd of 0.16 uM, potentiates TLX transcriptional repressive activity.

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生物&药学活性

TLX agonist 2 (Compound 31) is a small molecule agonist of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 0.1 uM and Kd of 0.16 uM, potentiates TLX transcriptional repressive activity.

物理化学性质&存储条件

分子量	453.43
分子式	C23H18F3N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(1,5-dimethyl-1H-pyrazole-3-carboxamido)-5-(trifluoromethyl)phenyl)quinoline-4-carboxamide

参考文献

1. Hank EC, et al. J Med Chem. 2026 Jun 25;69(12):14704-14721.

TLX agonist 2

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TLX agonist 2

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