TLX agonist 10

Chemical Structure : TLX agonist 10

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货号: PC-72812Not For Human Use, Lab Use Only.

TLX agonist 10 is potent, selective agonist of the orphan nuclear receptor tailless homologue (TLX, NR2E1) with pEC50 of 6.6.

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TLX agonist 10 is potent, selective agonist of the orphan nuclear receptor tailless homologue (TLX, NR2E1) with pEC50 of 6.6.
TLX agonist 10 is a valuable TLX agonist tool with submicromolar potency and high selectivity over related nuclear receptors, rendering it suitable for functional studies on TLX.

物理化学性质&存储条件

分子量	468.480
分子式	C25H23F3N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-butoxy-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)quinoline-4-carboxamide

参考文献

1. Giuseppe Faudone, et al. J Med Chem. 2022 Jan 6. doi: 10.1021/acs.jmedchem.1c01757.

TLX agonist 10

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TLX agonist 10

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