TLX agonist 1 | TLX agonist | Probechem Biochemicals

Chemical Structure : TLX agonist 1

CAS No.: 958323-31-4

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TLX agonist 1 (Compound ccrp2)

货号: PC-27591Not For Human Use, Lab Use Only.

TLX agonist 1 (Compound ccrp2) is a specific small molecule agonist of orphan nuclear receptor tailless (TLX, NR2E1), specifically binds to TLX LBD with Kd of 650 nM, potentiates TLX transcriptional repressive activity.

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生物&药学活性

TLX agonist 1 (Compound ccrp2) is a specific small molecule agonist of orphan nuclear receptor tailless (TLX, NR2E1), specifically binds to TLX LBD with Kd of 650 nM, potentiates TLX transcriptional repressive activity.
TLX agonist 1 does not bind two unrelated nuclear receptors ERβ and LXRβ.

物理化学性质&存储条件

分子量	374.49
分子式	C23H26N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-Benzhydrylpiperazin-1-yl)(1,5-dimethyl-1H-pyrazol-3-yl)methanone

参考文献

1. Benod C, et al. PLoS One. 2014 Jun 17;9(6):e99440.

TLX agonist 1 (Compound ccrp2)

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TLX agonist 1 (Compound ccrp2)

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