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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-TLR9 antagonist 38
TLR9 antagonist 38

Chemical Structure : TLR9 antagonist 38

CAS No.: 3105410-45-2

TLR9 antagonist 38

货号: PC-25546Not For Human Use, Lab Use Only.

TLR9 antagonist 38 is a highly potent, selective TLR9 antagonist with IC50 of 0.1 nM (hTLR9), >10,000-fold selectivity over hTLR2/4/5/7/8.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TLR9 antagonist 38 is a highly potent, selective TLR9 antagonist with IC50 of 0.1 nM (hTLR9), >10,000-fold selectivity over hTLR2/4/5/7/8.

    物理化学性质&存储条件

    分子量 455.61
    分子式 C28H33N5O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-(5-(4-((2-methoxybenzyl)amino)butyl)hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)quinoline-8-carbonitrile

    参考文献

    1. Xue Song, et al. ACS Med Chem Lett. 2025 Aug 26;16(9):1747-1755.

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