TLR 7/8 agonist 558 | TLR7/8 agonist | Probechem Biochemicals

Chemical Structure : TLR 7/8 agonist 558

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TLR 7/8 agonist 558 (TLR7/8 agonist 6)

货号: PC-25312Not For Human Use, Lab Use Only.

TLR 7/8 agonist 558 (TLR7/8 agonist 6) is a potent TLR7 and TLR8 small molecule agonist with EC50 of 0.18 uM and 5.34 uM respectively, stimulates TNFα, IFNγ, and IL-1β.

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生物&药学活性

TLR 7/8 agonist 558 (TLR7/8 agonist 6) is a potent TLR7 and TLR8 small molecule agonist with EC50 of 0.18 uM and 5.34 uM respectively, stimulates TNFα, IFNγ, and IL-1β.

物理化学性质&存储条件

分子量	417.51
分子式	C24H27N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinoline-7-carboxylate

参考文献

1. Bhatnagar S, et al. J Immunother. 2025 Aug 6. doi: 10.1097/CJI.0000000000000571.

2. Yang M, et al. Bioorg Med Chem Lett. 2022;59:128548.

TLR 7/8 agonist 558 (TLR7/8 agonist 6)

生物&药学活性

物理化学性质&存储条件

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TLR 7/8 agonist 558 (TLR7/8 agonist 6)

生物&药学活性

物理化学性质&存储条件

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