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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-TLR2 agonist C10
TLR2 agonist C10

Chemical Structure : TLR2 agonist C10

CAS No.: 3095426-02-8

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TLR2 agonist C10

货号: PC-28203Not For Human Use, Lab Use Only.

TLR2 agonist C10 is a potent, selective TLR2 agonist with EC50 of 35 nM, without activating TLR3, TLR4, TLR7 or TLR8.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TLR2 agonist C10 is a potent, selective TLR2 agonist with EC50 of 35 nM, without activating TLR3, TLR4, TLR7 or TLR8.
C10 induces the secretion of pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α, in human immune cells.

物理化学性质&存储条件

分子量 423.41
分子式 C19H16F3N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(5-(2-(methylamino)-5-(methylsulfonyl)phenyl)pyrimidin-2-yl)-5-(trifluoromethyl)phenol

参考文献

1. Zhu Y, et al. ACS Med Chem Lett. 2026 Aug 20;17(9):2017-2026.

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