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首页-小分子抑制剂&激动剂-Others-Other Targets-TJ191
TJ191

Chemical Structure : TJ191

CAS No.: 1522415-97-9

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TJ191 (TJ 191)

货号: PC-63231Not For Human Use, Lab Use Only.

TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM).

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50 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM).
TJ191 selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity).
TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells.

物理化学性质&存储条件

分子量 255.376
分子式 C13H21NO2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl 2-amino-5-heptylthiophene-3-carboxylate

参考文献

1. El-Gazzar A, et al. Oncotarget. 2017 Dec 15;9(5):6259-6269.

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