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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-TIPP-703
TIPP-703

Chemical Structure : TIPP-703

CAS No.: 1016893-72-3

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TIPP-703 (TIPP703)

货号: PC-23873Not For Human Use, Lab Use Only.

TIPP-703 is a potent, PPARα/δ/γ pan agonist with EC50 of 61/120/43 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TIPP-703 is a potent, PPARα/δ/γ pan agonist with EC50 of 61/120/43 nM respectively.
TIPP-703 stimulates adipocyte differentiation of murine preadipocyte 3T3-L1 cells.
TIPP-703 can activate various kinds of PPAR-regulated genes at the cellular level.

物理化学性质&存储条件

分子量 503.7
分子式 C32H41NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2s)-2-(4-Propoxy-3-{[({4-[(3s,5s,7s)-Tricyclo[3.3.1.1~3,7~]dec-1-Yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic Acid

参考文献

1. Kasuga J, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4525-8.

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